Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox10  SRY (sex determining region Y)-box 10   (Synonyms: gt, Sox21)
Results	Reference
1	J:310312 Abe M, Cox TC, Firulli AB, Kanai SM, Dahlka J, Lim KC, Engel JD, Clouthier DE, GATA3 is essential for separating patterning domains during facial morphogenesis. Development. 2021 Sep 1;148(17):dev199534
1	J:143626 Ai D, Fu X, Wang J, Lu MF, Chen L, Baldini A, Klein WH, Martin JF, Canonical Wnt signaling functions in second heart field to promote right ventricular growth. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9319-24
1	J:232560 Anderson MJ, Schimmang T, Lewandoski M, An FGF3-BMP Signaling Axis Regulates Caudal Neural Tube Closure, Neural Crest Specification and Anterior-Posterior Axis Extension. PLoS Genet. 2016 May;12(5):e1006018
1*	J:111609 Anderson RM, Stottmann RW, Choi M, Klingensmith J, Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev Dyn. 2006 Aug 7;235(9):2507-2520
1	J:104443 Antonellis A, Bennett WR, Menheniott TR, Prasad AB, Lee-Lin SQ, Green ED, Paisley D, Kelsh RN, Pavan WJ, Ward A, Deletion of long-range sequences at Sox10 compromises developmental expression in a mouse model of Waardenburg-Shah (WS4) syndrome. Hum Mol Genet. 2006 Jan 15;15(2):259-71
1	J:83662 Bachiller D, Klingensmith J, Shneyder N, Tran U, Anderson R, Rossant J, De Robertis EM, The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development. 2003 Aug;130(15):3567-78
1*	J:118344 Bennetts JS, Rendtorff ND, Simpson F, Tranebjaerg L, Wicking C, The coding region of TP53INP2, a gene expressed in the developing nervous system, is not altered in a family with autosomal recessive non-progressive infantile ataxia on chromosome 20q11-q13. Dev Dyn. 2007 Mar;236(3):843-52
1*	J:193413 Bildsoe H, Loebel DA, Jones VJ, Hor AC, Braithwaite AW, Chen YT, Behringer RR, Tam PP, The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function. Dev Biol. 2013 Feb 15;374(2):295-307
1	J:93195 Bogani D, Warr N, Elms P, Davies J, Tymowska-Lalanne Z, Goldsworthy M, Cox RD, Keays DA, Flint J, Wilson V, Nolan P, Arkell R, New semidominant mutations that affect mouse development. Genesis. 2004 Oct;40(2):109
1	J:88826 Brewer S, Feng W, Huang J, Sullivan S, Williams T, Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol. 2004 Mar 1;267(1):135-52
1	J:197199 Buckley DM, Burroughs-Garcia J, Lewandoski M, Waters ST, Characterization of the Gbx1-/- mouse mutant: a requirement for Gbx1 in normal locomotion and sensorimotor circuit development. PLoS One. 2013;8(2):e56214
1	J:152319 Calmont A, Ivins S, Van Bueren KL, Papangeli I, Kyriakopoulou V, Andrews WD, Martin JF, Moon AM, Illingworth EA, Basson MA, Scambler PJ, Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm. Development. 2009 Sep;136(18):3173-83
1*	J:124873 Carmona-Fontaine C, Acuna G, Ellwanger K, Niehrs C, Mayor R, Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopf1 secreted by the prechordal mesoderm. Dev Biol. 2007 Sep 15;309(2):208-21
1	J:231470 Chandler RL, Magnuson T, The SWI/SNF BAF-A complex is essential for neural crest development. Dev Biol. 2016 Mar 1;411(1):15-24
1	J:105025 Cheung M, Chaboissier MC, Mynett A, Hirst E, Schedl A, Briscoe J, The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell. 2005 Feb;8(2):179-92
1	J:104151 Coles EG, Gammill LS, Miner JH, Bronner-Fraser M, Abnormalities in neural crest cell migration in laminin alpha5 mutant mice. Dev Biol. 2006 Jan 1;289(1):218-28
1	J:299019 Dash S, Bhatt S, Sandell LL, Seidel CW, Ahn Y, Krumlauf RE, Trainor PA, The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development. Front Physiol. 2020;11:531933
1	J:143845 Davy A, Soriano P, Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Dev Biol. 2007 Apr 1;304(1):182-93
1*	J:78768 De Bellard M, Ching W, Gossler A, Bronner-Fraser M, Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice. Dev Biol. 2002 Sep 1;249(1):121
1	J:334461 De Bono C, Liu Y, Ferrena A, Valentine A, Zheng D, Morrow BE, Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development. Nat Commun. 2023 Mar 21;14(1):1551
1*	J:284772 DiStasio A, Paulding D, Chaturvedi P, Stottmann RW, Nubp2 is required for cranial neural crest survival in the mouse. Dev Biol. 2020 Feb 15;458(2):189-199
1	J:112900 Dixon J, Jones NC, Sandell LL, Jayasinghe SM, Crane J, Rey JP, Dixon MJ, Trainor PA, Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities. Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13403-8
1	J:152832 Dupe V, Pellerin I, Retinoic acid receptors exhibit cell-autonomous functions in cranial neural crest cells. Dev Dyn. 2009 Sep 23;238(10):2701-2711
1*	J:229008 Escot S, Blavet C, Faure E, Zaffran S, Duband JL, Fournier-Thibault C, Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations. Development. 2016 Feb 15;143(4):582-8
1*	J:116335 Gammill LS, Gonzalez C, Bronner-Fraser M, Neuropilin 2/semaphorin 3F signaling is essential for cranial neural crest migration and trigeminal ganglion condensation. J Neurobiol. 2006 Oct 20;67(1):47-56
1	J:104892 Gammill LS, Gonzalez C, Gu C, Bronner-Fraser M, Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development. 2006 Jan;133(1):99-106
1*	J:71033 Gavalas A, Trainor P, Ariza-McNaughton L, Krumlauf R, Synergy between Hoxa1 and Hoxb1: the relationship between arch patterning and the generation of cranial neural crest. Development. 2001 Aug;128(15):3017-27
1	J:265720 Gonzalez Malagon SG, Lopez Munoz AM, Doro D, Bolger TG, Poon E, Tucker ER, Adel Al-Lami H, Krause M, Phiel CJ, Chesler L, Liu KJ, Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus. Nat Commun. 2018 Mar 19;9(1):1126
1	J:153219 Grossmann KS, Wende H, Paul FE, Cheret C, Garratt AN, Zurborg S, Feinberg K, Besser D, Schulz H, Peles E, Selbach M, Birchmeier W, Birchmeier C, The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16704-9
1	J:191738 Harel I, Maezawa Y, Avraham R, Rinon A, Ma HY, Cross JW, Leviatan N, Hegesh J, Roy A, Jacob-Hirsch J, Rechavi G, Carvajal J, Tole S, Kioussi C, Quaggin S, Tzahor E, Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18839-44
1	J:202450 He F, Soriano P, A Critical Role for PDGFRalpha Signaling in Medial Nasal Process Development. PLoS Genet. 2013 Sep;9(9):e1003851
1*	J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42
1*	J:333013 Huang T, Hou Y, Wang X, Wang L, Yi C, Wang C, Sun X, Tam PKH, Ngai SM, Sham MH, Burns AJ, Chan WY, Direct Interaction of Sox10 With Cadherin-19 Mediates Early Sacral Neural Crest Cell Migration: Implications for Enteric Nervous System Development Defects. Gastroenterology. 2022 Jan;162(1):179-192.e11
1	J:92220 Inoue T, Hatayama M, Tohmonda T, Itohara S, Aruga J, Mikoshiba K, Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives. Dev Biol. 2004 Jun 1;270(1):146-62
1	J:102844 Ishii M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE Jr, Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development. 2005 Nov;132(22):4937-50
1	J:192179 Jacques-Fricke BT, Roffers-Agarwal J, Gammill LS, DNA methyltransferase 3b is dispensable for mouse neural crest development. PLoS One. 2012;7(10):e47794
1*	J:133682 Jones NC, Lynn ML, Gaudenz K, Sakai D, Aoto K, Rey JP, Glynn EF, Ellington L, Du C, Dixon J, Dixon MJ, Trainor PA, Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function. Nat Med. 2008 Feb;14(2):125-33
1	J:229073 Kam MK, Cheung MC, Zhu JJ, Cheng WW, Sat EW, Tam PK, Lui VC, Perturbation of Hoxb5 signaling in vagal and trunk neural crest cells causes apoptosis and neurocristopathies in mice. Cell Death Differ. 2014 Feb;21(2):278-89
1	J:263685 Kitami K, Kitami M, Kaku M, Wang B, Komatsu Y, BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development. PLoS Genet. 2018 May;14(5):e1007340
1	J:229187 Kurosaka H, Trainor PA, Leroux-Berger M, Iulianella A, Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling. PLoS One. 2015;10(3):e0120821
1	J:159224 Kurosaka S, Leu NA, Zhang F, Bunte R, Saha S, Wang J, Guo C, He W, Kashina A, Arginylation-dependent neural crest cell migration is essential for mouse development. PLoS Genet. 2010;6(3):e1000878
1	J:236825 Langer D, Martianov I, Alpern D, Rhinn M, Keime C, Dolle P, Mengus G, Davidson I, Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation. Nat Commun. 2016 Mar 30;7:11063
1*	J:208825 Lassiter RN, Stark MR, Zhao T, Zhou CJ, Signaling mechanisms controlling cranial placode neurogenesis and delamination. Dev Biol. 2014 May 1;389(1):39-49
1	J:226395 Lewis AE, Hwa J, Wang R, Soriano P, Bush JO, Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol. 2015 Oct 15;406(2):186-95
1	J:132940 Lin W, Zhang Z, Srajer G, Chen YC, Huang M, Phan HM, Dent SY, Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos. Dev Dyn. 2008 Apr;237(4):928-40
1	J:241570 Lumb R, Buckberry S, Secker G, Lawrence D, Schwarz Q, Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels. BMC Dev Biol. 2017 Apr 13;17(1):5
1	J:217420 Lumb R, Wiszniak S, Kabbara S, Scherer M, Harvey N, Schwarz Q, Neuropilins define distinct populations of neural crest cells. Neural Dev. 2014;9(1):24
1*	J:106405 Mackay DR, Hu M, Li B, Rheaume C, Dai X, The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol. 2006 Mar 1;291(1):38-52
1	J:187616 Maden CH, Gomes J, Schwarz Q, Davidson K, Tinker A, Ruhrberg C, NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. Dev Biol. 2012 Sep 15;369(2):277-85
1	J:311992 Mandalos N, Rhinn M, Granchi Z, Karampelas I, Mitsiadis T, Economides AN, Dolle P, Remboutsika E, Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development. Front Physiol. 2014;5:345
1	J:235736 Masek J, Machon O, Korinek V, Taketo MM, Kozmik Z, Tcf7l1 protects the anterior neural fold from adopting the neural crest fate. Development. 2016 Jun 15;143(12):2206-16
1	J:180974 Meng H, Yuan Y, Lee VM, Loss of Sphingosine kinase 1/S1P signaling impairs cell growth and survival of neurons and progenitor cells in the developing sensory ganglia. PLoS One. 2011;6(11):e27150
1	J:162916 Moore BA, Gonzalez Aviles GD, Larkins CE, Hillman MJ, Caspary T, Mitochondrial retention of Opa1 is required for mouse embryogenesis. Mamm Genome. 2010 Aug;21(7-8):350-60
1*	J:96463 Moraes F, Novoa A, Jerome-Majewska LA, Papaioannou VE, Mallo M, Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development. Mech Dev. 2005 Feb;122(2):199-212
1*	J:79480 Natarajan D, Marcos-Gutierrez C, Pachnis V, de Graaff E, Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis. Development. 2002 Nov;129(22):5151-60
1*	J:90276 Ota MS, Loebel DA, O'Rourke MP, Wong N, Tsoi B, Tam PP, Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells. Dev Dyn. 2004 Jun;230(2):216-28
1	J:282947 Poncet N, Halley PA, Lipina C, Gierlinski M, Dady A, Singer GA, Febrer M, Shi YB, Yamaguchi TP, Taylor PM, Storey KG, Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos. EMBO Rep. 2020 Jan 7;21(1):e48469
1*	J:50203 Pusch C, Hustert E, Pfeifer D, Sudbeck P, Kist R, Roe B, Wang Z, Balling R, Blin N, Scherer G, The SOX10/Sox10 gene from human and mouse: sequence, expression, and transactivation by the encoded HMG domain transcription factor. Hum Genet. 1998 Aug;103(2):115-23
1	J:169829 Pyrgaki C, Liu A, Niswander L, Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Dev Biol. 2011 May 1;353(1):38-49
1	J:93020 Remacle S, Abbas L, De Backer O, Pacico N, Gavalas A, Gofflot F, Picard JJ, Rezsohazy R, Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo. Mol Cell Biol. 2004 Oct;24(19):8567-75
1	J:195357 Roeseler DA, Sachdev S, Buckley DM, Joshi T, Wu DK, Xu D, Hannink M, Waters ST, Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2. PLoS One. 2012;7(11):e47366
1	J:297650 Roeseler DA, Strader L, ANderson MJ, Waters ST, Gbx2 is required for the migration and survival of a subpopulation of trigeminal cranial neural crest cells. J Dev Biol. 2020;8(33)
1	J:149562 Roffers-Agarwal J, Gammill LS, Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation. Development. 2009 Jun;136(11):1879-88
1*	J:240035 Roux M, Laforest B, Eudes N, Bertrand N, Stefanovic S, Zaffran S, Hoxa1 and Hoxb1 are required for pharyngeal arch artery development. Mech Dev. 2017 Feb;143:1-8
1*	J:226957 Saldana-Caboverde A, Perera EM, Watkins-Chow DE, Hansen NF, Vemulapalli M, Mullikin JC, Nisc Comparative Sequencing Program, Pavan WJ, Kos L, The transcription factors Ets1 and Sox10 interact during murine melanocyte development. Dev Biol. 2015 Nov 15;407(2):300-12
1	J:231654 Sanchez-Ferras O, Bernas G, Farnos O, Toure AM, Souchkova O, Pilon N, A direct role for murine Cdx proteins in the trunk neural crest gene regulatory network. Development. 2016 Apr 15;143(8):1363-74
1	J:171522 Sandell LL, Iulianella A, Melton KR, Lynn M, Walker M, Inman KE, Bhatt S, Leroux-Berger M, Crawford M, Jones NC, Dennis JF, Trainor PA, A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development. Genesis. 2011 Apr;49(4):342-59
1	J:161587 Schleiffarth JR, Person AD, Martinsen BJ, Sukovich DJ, Neumann A, Baker CV, Lohr JL, Cornfield DN, Ekker SC, Petryk A, Wnt5a is required for cardiac outflow tract septation in mice. Pediatr Res. 2007 Apr;61(4):386-91
1*	J:149474 Schwarz Q, Maden CH, Davidson K, Ruhrberg C, Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia. Development. 2009 Jun;136(11):1785-9
1	J:209482 Schwarz Q, Maden CH, Vieira JM, Ruhrberg C, Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6164-9
1	J:134486 Schwarz Q, Vieira JM, Howard B, Eickholt BJ, Ruhrberg C, Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells. Development. 2008 May;135(9):1605-13
1	J:242073 Seberg HE, Van Otterloo E, Loftus SK, Liu H, Bonde G, Sompallae R, Gildea DE, Santana JF, Manak JR, Pavan WJ, Williams T, Cornell RA, TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PLoS Genet. 2017 Mar;13(3):e1006636
1*	J:77801 Soo K, O'Rourke MP, Khoo PL, Steiner KA, Wong N, Behringer RR, Tam PP, Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryo. Dev Biol. 2002 Jul 15;247(2):251-70
1*	J:45117 Southard-Smith EM, Kos L, Pavan WJ, Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet. 1998 Jan;18(1):60-4
1	J:229586 Tondeleir D, Noelanders R, Bakkali K, Ampe C, Beta-actin is required for proper mouse neural crest ontogeny. PLoS One. 2014;9(1):e85608
1	J:105216 Trokovic N, Trokovic R, Partanen J, Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm. Int J Dev Biol. 2005;49(7):797-805
1	J:175465 Urness LD, Bleyl SB, Wright TJ, Moon AM, Mansour SL, Redundant and dosage sensitive requirements for Fgf3 and Fgf10 in cardiovascular development. Dev Biol. 2011 Aug 15;356(2):383-97
1*	J:73282 Watari N, Kameda Y, Takeichi M, Chisaka O, Hoxa3 regulates integration of glossopharyngeal nerve precursor cells. Dev Biol. 2001 Dec 1;240(1):15-31
1	J:203994 Wiszniak S, Kabbara S, Lumb R, Scherer M, Secker G, Harvey N, Kumar S, Schwarz Q, The ubiquitin ligase Nedd4 regulates craniofacial development by promoting cranial neural crest cell survival and stem-cell like properties. Dev Biol. 2013 Nov 15;383(2):186-200
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1*	J:179369 Zhang Y, Kim TH, Niswander L, Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity. Genes Dev. 2012 Jan 1;26(1):69-81
1*	J:122594 Zohn IE, Anderson KV, Niswander L, The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure. Dev Biol. 2007 Jun 1;306(1):208-21
1	J:94396 Zou D, Silvius D, Fritzsch B, Xu PX, Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Development. 2004 Nov;131(22):5561-72